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Type: Goat IgG
 
Applications: IHC; WB
ICC=Immunocytochemistry; IF=Immunofluorescence; IHC=Immunohistochemistry; WB=Western blotting; FC=Flow Cytometry; IP=Immunoprecipitation; E=ELISA; NB=Neutralization of Bioactivity; FACS; All Fluorecent Images;
Species Reactivity: R
B=Bovine; Ca=Cat; Ch=Chicken; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Ze=Zebrafish; na
Format: Affinity Purified - liquid
 
Immunogen: E. coli-derived, recombinant rat interleukin 2 (rrIL-2).
 
Description/Data:

Interleukin 2 (IL-2) was initially identified as a T cell growth factor that is produced by T cells following activation by mitogens or antigens. Since then, it has also been shown to stimulate the growth and differentiation of B cells, natural killer (NK) cells, lymphocyte activated killer (LAK) cells, monocytes/macrophages and oligodendrocytes. At the amino acid sequence level, there is approximately 60-90% similarity between species. Mature human IL-2 shares 60%, 72%, 72%, 78%, and 86% similarities with mouse, equine, porcine, feline, and canine, respectively.

Image: IL-2  staining of  rat spleen tissue section from DA rat suffering from collagen-induced arthritis. Cells were stained using DAB as the peroxidase substrate.