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| Catalog Number | Size | Price (USD) | Shopping Cart |
|---|---|---|---|
| GT15191 | 100 ug | $365.00 | Buy Now | Add to Cart |
Type: Goat IgG
Applications: IHC; WB; E
ICC=Immunocytochemistry; IF=Immunofluorescence; IHC=Immunohistochemistry; WB=Western blotting; FC=Flow Cytometry; IP=Immunoprecipitation; E=ELISA; NB=Neutralization of Bioactivity; FACS; All Fluorecent Images;
Species Reactivity: H; R
B=Bovine; Ca=Cat; Ch=Chicken; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Ze=Zebrafish; na
Format: Affinity Purified - liquid
Immunogen: Purified, NS0-derived, recombinant mouse Chordin (rmChordin) (aa 27 - 948).
Description/Data:
Chordin is an extracellular antagonist of BMP signaling which is thought to readily diffuse in tissues, thus forming gradients of BMP inhibition that result in reciprocal gradients of BMP signaling thus impacting cell fate determination along the embryonic dorsoventral axis.
This antibody will block > 95% of the binding of 100 ng/mL of rhBMP-4 to immobilized rmChordin. (100 μL of 5 g/mL was coated in each well) in a functional ELISA. 50% inhibition occurs at an antibody concentration of approximately 3 - 12 μg/mL.
Image: Chordin staining of cryostat tissue sections of mouse liver. Tissues were stained using Goat (red-brown) and counterstained with hematoxylin (blue).