|
| Catalog Number | Size | Price (USD) | Shopping Cart |
|---|---|---|---|
| RA30037 | 50 ug | $365.00 | Buy Now | Add to Cart |
Type: Rabbit IgG
Applications: IHC
ICC=Immunocytochemistry; IF=Immunofluorescence; IHC=Immunohistochemistry; WB=Western blotting; FC=Flow Cytometry; IP=Immunoprecipitation; E=ELISA; NB=Neutralization of Bioactivity; FACS; All Fluorecent Images;
Species Reactivity: H
B=Bovine; Ca=Cat; Ch=Chicken; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Ze=Zebrafish; na
Format: Affinity Purified - liquid
Immunogen: KLH Coupled Synthetic peptide corresponding to the internal domain of the human ERK1.
Description/Data:
ERK1 and ERK2 (also known as MAPK3 and MAPK1) are 44- and 42-kDa Ser/Thr kinases, respectively. They are part of the Ras-Raf-ERK signal transduction cascade often found downstream of growth factor receptor activation. ERK1 and ERK2 were initially isolated and cloned as kinases activated in response to insulin and NGF. They are expressed in most, if not all, mammalian tissues. Dual threonine and tyrosine phosphorylation activate both ERKs, at Thr202/Tyr204 for human ERK1 and Thr185/Tyr187 for human ERK2.
Image: ERK1 staining of Human Neurons and Glia. Paraffin-Embedded Formalin-Fixed Tissue.
Related Reagents to consider:
phospho-ERK1/2-Rabbit Monoclonal
Neurotrophin and Growth Factors