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Type: Rabbit IgG
 
Applications: ICC; IHC; WB
ICC=Immunocytochemistry; IF=Immunofluorescence; IHC=Immunohistochemistry; WB=Western blotting; FC=Flow Cytometry; IP=Immunoprecipitation; E=ELISA; NB=Neutralization of Bioactivity; FACS; All Fluorecent Images;
Species Reactivity: M; R
B=Bovine; Ca=Cat; Ch=Chicken; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Ze=Zebrafish; na
Format: Affinity Purified - liquid
 
Immunogen: AAPPQNENAEDAK
 
Description/Data:

Metabotropic glutamate receptors (mGluRs) are G-protein coupled receptors activated by glutamate. Based on sequence similarity, transduction mechanisms and agonist potencies, mGluRs are subdivided into three groups: mGluR1/mGluR5, mGluR2/mGluR3, and mGluR4/mGluR6/mGluR7/mGluR8. mGluRs are widely distributed throughout the nervous system and are expressed by both neurons and glial cells. mGluRs have been suggested to play a variety of functional roles, among which is involvement in synaptic plasticity underlying learning and memory as well as chronic pain.

IHC Image: Staining of mouse nob rescue retinal sections.  

WB Image: Mouse retinal lysates. Courtesy of Megan A. Foreman, University of Birmingham.

mGluR6-Customer Data and Publications.

Note: A customer found a band in the 60-70 kDa range corresponding to the mGluR6 precursor.

 

More Links:

mGluR6

Neurotransmission Research Antibodies -GPCRs, Ligand Gated Ion Channels, Biogenic Amines and more

Pain and Inflammation Research Antibodies

Vision and Retina Research Antibodies

Primary Neurons and Astrocytes -Primary human, rat and mouse neurons and astrocytes by Category

Image: mGluR6 staining of GluR6 in trapezoid body in mouse brain using anti-rabbit Cy3 conjugated secondary antibodies (red color). DAPI was used to counterstain cell nuclei. Dilution 1:30. Tissue was mounted to slide using i-BRITE Plus anti fade media.