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| Catalog Number | Size | Price (USD) | Shopping Cart |
|---|---|---|---|
| CH14100 | 50 ul | $215.00 | Buy Now | Add to Cart |
| CH14100 | 150 ul | $475.00 | Buy Now | Add to Cart |
Calcitonin gene-related peptide (CGRP) is present in C-cells of the thyroid and in central and peripheral nerves. CGRP has several important physiologic roles: it is a potent vasodilator, and can affect the force and rate of heart beat; it can modulate acetylcholine receptor function at the neuromuscular junction; it has been demonstrated to block tolerance to morphine; and it can modulate antigen presentation in Langerhans cells in the skin.
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Image: Expression of calcitonin gene-related peptide (CGRP) and SNAP-25 in trigeminal ganglion neurons. The expression of CGRP (A) and SNAP-25 (B) are shown in the entire trigeminal ganglion obtained from an untreated adult animal. At higher magnification, neuronal processes(arrows) expressing both CGRP (C) and SNAP-25 (D)that extend from neuronal cell bodies in one cluster to another cluster are observed. Neuronal processes expressing SNAP-25 are also observed within neuronal clusters (E). Headache: The Journal of Head and Face Pain, Volume 47, Issue 7, Page 1008-1023, Jul 2007, doi: 10.1111/j.1526-4610.2007.00854.x