BMP-10

There are at least 20 structurally and functionally related BMPs, which are members of the TGF-beta superfamily. BMPs were originally identified as protein regulators of cartilage and bone formation. They are also involved in embryogenesis and morphogenesis of various tissues and organs. BMPs regulate the growth, differentiation, chemotaxis and apoptosis of various cell types, including mesenchymal cells, epithelial cells, hematopoietic cells and neuronal cells. Similar to other TGF-beta family proteins, BMPs are highly conserved across animal species.

Data strongly suggest that BMP10 is an essential component in modulating cardiomyocyte proliferation and maturation during cardiac ventricular development.and has recently been implicated in postnatal cardiac hypertrophy.

Image: BMP10  staining of paraffin embedded human cardiac tissue.

Other Reagents to Consider:

All Stem Cell Reagents

Proteins:

BMP-2, Catalog#: PR15013

BMP-2, Carrier Free

BMP-2, E.Coli Expressed

BMP-2, E. Coli Expressed, Carrier Free

BMP-2, Catalog#: PR27023

BMP-4, Catalog #:PR27024

BMP-4, Catalog#: PR15015 

BMP-4, Carrier Free

BMP-6

BMP-7

BMP-R Type 1A

All Proteins

Antibodies

BMP-1/PCP

BMP-2 Inducible Kinase (BIKE)

BMP-2/4

BMP-3b/GDF-10

BMP-3

BMP-4

BMP-5

BMP-5 Monoclonal

BMP-6

BMP-8

Chordin

GDF-3

GDF-5

GDF-8/Myostatin

BMP Proteins

Noggin

All Stem Cell Reagents

Neurotrophins/Growth Factors

Neuron/Glial Markers

Diabetes/Obesity Antibodies

Neurodegenerative Disease Antibodies

Cancer Antibodies