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Type: Mouse IgG
 
Applications: IHC; FC
ICC=Immunocytochemistry; IF=Immunofluorescence; IHC=Immunohistochemistry; WB=Western blotting; FC=Flow Cytometry; IP=Immunoprecipitation; E=ELISA; NB=Neutralization of Bioactivity; FACS; All Fluorecent Images;
Species Reactivity: H
B=Bovine; Ca=Cat; Ch=Chicken; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Ze=Zebrafish; na
Format: Protein G Purified - liquid
 
Immunogen: Hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a Balb/c mouse inoculated with CC chemokine receptor 5 (hCCR5) transfected NS0 mouse myeloma cells.
 
Description/Data:

Chemokine receptors are seven-transmembrane domain G-protein coupled receptors that mediate the biological activities of chemokines. Most of these receptors exhibit promiscuous binding properties whereby several different chemokines signal through the same receptor. They are named according to the chemokine subfamily they bind. There are currently eleven CC-specific receptors designated CCR1 to CCR11.

Image: CCR5 staining of a section of human dorsal root ganglion (DRG). The tissue was stained using Vectastain-ABC-Peroxidase Kit and AEC substrate (red), and counterstained with hematoxylin (blue).

Image: CCR5 staining of  cryostat tissue sections of human lymph node  (dilution: 25 µg/mL) .Tissues were stained using antimouse ABC-HRP and AEC substrate (red) and counterstained with hematoxylin (blue).