Tested, Characterized and Research Ready
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MO15029500 ug$325.00Buy Now | Add to Cart
MO1502950 ug$49.00   $125.00Buy Now | Add to Cart
 
Type: Rat IgG
 
Applications: IHC; WB; E
ICC=Immunocytochemistry; IF=Immunofluorescence; IHC=Immunohistochemistry; WB=Western blotting; FC=Flow Cytometry; IP=Immunoprecipitation; E=ELISA; NB=Neutralization of Bioactivity; FACS; All Fluorecent Images; ; HPLC=High Performance Liquid Chromatography; FPLC=Fast Protein Liquid Chromatography
Species Reactivity: M; R
B=Bovine; Ca=Cat; Ch=Chicken; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Ze=Zebrafish; na
Format: Protein G Purified - liquid
 
Immunogen: Recombinant mouse RAGE
 
Description/Data:

RAGE (receptor for advanced glycation end products) is a multiligand type I transmembrane glycoprotein belonging to the immunoglobulin (Ig) superfamily. RAGE ligands include advanced glycation end products (AGEs), amyloid-beta (A beta) peptide, HMG-1 (also known as Amphoterin), and several members of the S100 protein superfamily. RAGE has potential involvement in several pathological processes including diabetes, Alzheimer's disease (AD), systemic amyloidosis, and tumor growth. RAGE may also mediate several physiological functions such as neuronal outgrowth, survival, and regeneration, and play a part in pro-inflammatory reactions.