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| Catalog Number | Size | Price (USD) | Shopping Cart |
|---|---|---|---|
| RA30028 | 50 ug | $365.00 | Buy Now | Add to Cart |
Type: Rabbit IgG
Applications: IHC
ICC=Immunocytochemistry; IF=Immunofluorescence; IHC=Immunohistochemistry; WB=Western blotting; FC=Flow Cytometry; IP=Immunoprecipitation; E=ELISA; NB=Neutralization of Bioactivity; FACS; All Fluorecent Images;
Species Reactivity: H
B=Bovine; Ca=Cat; Ch=Chicken; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Ze=Zebrafish; na
Format: Affinity Purified - liquid
Immunogen: KLH Coupled Synthetic Peptide- internal domain of human Wnt5b.
Description/Data:
Human Wnt-1 is a 41 kDa, 370 aa protein that contains four potential N-linked glycosylation sites plus 23 cysteines. When secreted, it exists as a 343 aa glycoprotein with a molecular weight of 42 to 48 kDa. Twelve of the cysteines lie in the last 70 aa of the molecule, and two of these contribute to potential N-linked glycosylation sites.
Wnt1 is involved in development of the neural crest and is suspected to play a role in the genesis of dopmanergic neurons in the developing midbrain. Elevated levels of the Wnt1 protein is associated with tumorigenesis and is present in numerous breast cancers.
Image: Wnt1 staining of Human Cortex. Formalin-Fixed Paraffin-Embedded (FFPE).