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Type: Rabbit IgG
 
Applications: IHC; WB; IP
ICC=Immunocytochemistry; IF=Immunofluorescence; IHC=Immunohistochemistry; WB=Western blotting; FC=Flow Cytometry; IP=Immunoprecipitation; E=ELISA; NB=Neutralization of Bioactivity; FACS; All Fluorecent Images;
Species Reactivity: H; M; Pr; R
B=Bovine; Ca=Cat; Ch=Chicken; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Ze=Zebrafish; na
Format: Affinity Purified - liquid
 
Immunogen: Synthetic peptide (KLH-coupled) derived from a sequence of human AP-2?.
 
Description/Data:

The sequence-specific transcription factor activator protein 2α (AP-2α) is required for normal growth and morphogenesis during mammalian development. This includes development of the Neural Crest.

Decreased or loss of AP-2α expression has been observed in many different types of human cancers including breast cancer, ovarian cancer, melanoma and prostate cancer.

IHC Image: AP-2α atining of paraffin-embedded human lung carcinoma.

WB Image: Western blot analysis of extracts from various cell lines