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| Catalog Number | Size | Price (USD) | Shopping Cart |
|---|---|---|---|
| PR27081-2 | 2 ug | $75.00 | Buy Now | Add to Cart |
| PR27081-10 | 10 ug | $155.00 | Buy Now | Add to Cart |
Type: Protein
Species Reactivity: H
B=Bovine; Ca=Cat; Ch=Chicken; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Ze=Zebrafish; na
Format: liquid - liquid
Description/Data:
Syntaxin-1, synaptobrevin, and SNAP25 cooperate to form the SNARE complex, which is needed for synaptic vesicle docking and fusion SNPH is a neuron-specific protein originally characterized as a binding partner of syntaxin-1. SNPH participates with SNAP25 for the binding to Syntaxin-1 and prevents the construction of the SNARE core complex, thus manageling free syntaxin-1 availability for the assembly of the SNARE complex and potentially regulating synaptic vesicle exocytosis. Expression Syntaphilin appears to be brain-specific. SNPH is an inhibitor of both SNARE-based fusion and dynamin-mediated endocytosis.
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Primary Neurons and Astrocytes-Primary human, rat and mouse neurons and astrocytes |