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| Catalog Number | Size | Price (USD) | Shopping Cart |
|---|---|---|---|
| PR27113-5 | 5 ug | $75.00 | Buy Now | Add to Cart |
| PR27113-25 | 25 ug | $175.00 | Buy Now | Add to Cart |
Type: Protein
Species Reactivity: H
B=Bovine; Ca=Cat; Ch=Chicken; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Ze=Zebrafish; na
Description/Data:
IL17 is a proinflammatory cytokine produced by activated T cells. IL-17 regulates the activities of NF-kappaB and mitogen-activated protein kinases. Interleukin-17 can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. It is also suspected to play a role in Autism.