Tested, Characterized and Research Ready
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RA15042100 ug$365.00Buy Now | Add to Cart
 
Type: Rabbit IgG
 
Applications: IHC; WB
ICC=Immunocytochemistry; IF=Immunofluorescence; IHC=Immunohistochemistry; WB=Western blotting; FC=Flow Cytometry; IP=Immunoprecipitation; E=ELISA; NB=Neutralization of Bioactivity; FACS; All Fluorecent Images;
Species Reactivity: H; M; R
B=Bovine; Ca=Cat; Ch=Chicken; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Ze=Zebrafish; na
Format: Affinity Purified - liquid
 
Immunogen: KLH coupled synthetic peptide CEPEAEAEPEPELE PEPDPEP corresponding to amino acids 176 - 195 of human ARC an inhibitor of apoptosis. Cysteine was added to the amino-terminal for coupling to KLH and for coupling to affinity matrix.
 
Description/Data:

ARC [Apoptosis Repressor with CARD (Caspase-recruitment Domain)] is a 29 kDa cytosolic protein containing an N-terminal CARD joined to a C-terminal region rich in proline and glutamic acid. The expression of human ARC is primarily restricted to skeletal muscle and cardiac tissue. ARC inhibits apoptosis induced by Caspase-8.

ARC Staining in Human Breast Cancer Tissue (a-f). ARC IHC with Antiserum Against Residues 176-195. Images Courtesy of Isabelle Mercier, Albert Einstein College of Medicine.

ARC: Customer Data and Publications.

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Apoptosis Research Reagents-Apoptosis Categories-includes: detection kits, antibodies and proteins